5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine

5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine - Names and Identifiers

Name	5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine
Synonyms	5-Chloro-3-iodo-6-azaindole 5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine 1H-pyrrolo[2,3-c]pyridine, 5-chloro-3-iodo-
CAS	1190310-51-0
EINECS	200-258-5
InChI	InChI=1S/C7H4ClIN2/c8-7-1-4-5(9)2-10-6(4)3-11-7/h1-3,10H

5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine - Physico-chemical Properties

Molecular Formula	C7H4ClIN2
Molar Mass	278.48
Density	2.156
Boling Point	415.4±40.0 °C(Predicted)
pKa	12.25±0.40(Predicted)
Storage Condition	2-8°C(protect from light)

5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine - Introduction

5-Chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine is an organic compound with the formula C9H4ClIN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 5-Chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine is a white to pale yellow crystalline solid.
-Melting point: Its melting point is about 250-255 degrees Celsius.
-Solubility: 5-chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine has good solubility in polar solvents, such as ethanol, dimethyl sulfoxide and N,N-dimethylformamide.

Use:
-5-Chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine is used in the preparation of catalysts and intermediates for the synthesis of important organic compounds in organic synthesis.
-It can also be used to prepare polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbon derivatives containing a quaternary pentylenetetraketone core.

Preparation Method:
The preparation method of-5-chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine can be completed by the catalytic coupling reaction between iodobenzene and 2,4, 6-trifluorocarbonate. This reaction is usually carried out in an organic solvent and requires a temperature higher than normal temperature.

Safety Information:
-5-Chloro-3-iodo-1H-pyrrolo [2,3-c] pyridine can be used as a transition metal ligand catalyst in catalytic reactions and is therefore generally not considered to be significantly hazardous.
-However, as an organic compound, it may cause irritation and toxicity to the human body. During operation, appropriate safety measures should be taken, such as wearing protective glasses, gloves and laboratory clothing, and operating in a well-ventilated environment. If the skin or eyes are touched, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15